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Urinary Incontinence -- US Government Wiew

 

Urinary Incontinence (*)

(*)Urinary Incontinence in Adults: Acute and Chronic Management, U.S. Department of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research

UI is a voiding dysfunction that affects approximately 13 million Americans, with the highest prevalence in the elderly in both community and institutional settings (National Kidney and Urologic Diseases Advisory Board, 1994). The high prevalence of UI and its significant adverse physical, psychological, and financial effects clearly justify more aggressive efforts to identify, evaluate, and treat UI in all settings. Growing evidence indicates that appropriate management can reduce the morbidity and cost of UI, particularly in institutionalized populations (Ouslander, Palmer, Rovner, et al., 1993).

Although the prevalence of UI increases with age, UI should not be considered a normal part of the aging process. Reported prevalence rates of UI vary considerably, depending on the population studied, the definition of UI, and how the information is obtained (Diokno, Brock, Herzog, et al., 1990). Among the population between 15 and 64 years of age, the prevalence of UI in men ranges from 1.5 to 5 percent and in women from 10 to 30 percent (Burgio, Matthews, and Engel, 1991; Harrison and Memel, 1994). Although UI is usually regarded as a condition affecting older multiparous women, it is also common in young, nulliparous women, particularly during physical activity (Bo, Maehlum, Oseid, et al., 1989; Nygaard, Thompson, Svengalis, et al., 1994).

For noninstitutionalized persons older than 60 years of age, the prevalence of UI ranges from 15 to 35 percent, with women having twice the prevalence of men. Between 25 and 30 percent of those identified as incontinent have frequent incontinence episodes, usually daily or weekly (Burgio, Matthews, and Engel, 1991; Diokno, Brock, Brown, et al., 1986).

Survey data from caregivers of the elderly show that approximately 53 percent of the homebound elderly are incontinent (Noelker, 1987). A random sampling of hospitalized elderly patients identified 11 percent as having persistent UI at admission and 23 percent at discharge (Palmer, McCormick, Langford, et al., 1992).

UI is generally recognized as one of the major causes of institutionalization of the elderly. Among the more than 1.5 million nursing facility residents, the prevalence of UI is 50 percent or greater, with the majority of nursing home residents having frequent UI (Ouslander, Kane, and Abrass, 1982; Palmer, German, and Ouslander, 1991). The annual incidence of UI in nursing home residents who are admitted continent was recently reported to be 27 percent and is higher in males; it is strongly associated with dementia, fecal incontinence, and inability to walk and transfer independently (Ouslander, Kane, and Abrass, 1982; Palmer, German, and Ouslander, 1991).

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Quality of Life

UI imposes a significant psychosocial impact on individuals, their families, and caregivers. UI results in a loss of self-esteem and a decrease in ability to maintain an independent lifestyle. Dependence on caregivers for activities of daily life increases as incontinence worsens. Consequently, excursions outside the home, social interaction with friends and family, and sexual activity may be restricted or avoided entirely (Grimby, Milsom, Molander, et al., 1993; Harris, 1986; Noelker, 1987). Quality-of-life and symptom distress questionnaires for women with UI have been validated for use (Shumaker, Wyman, Uebersax, et al., 1994; Uebersax, Wyman, Shumaker, et al., 1995).

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Underreporting/Undertreatment

Fewer than half of individuals with UI living in the community consult health care providers about the problem (Burgio, Ives, Locher, et al., 1994). The reasons for this could be the availability of absorbent products, low expectations of benefit from reporting the condition to health care providers, and lack of information regarding management options. There is a lack of understanding about UI, especially among men, those age 85 or older, and those with lower levels of education (Branch, Walker, Wetle, et al., 1994).

Studies show significant variation in performance of adequate examination, assessment, and management of UI. UI is often undetected and underreported by hospital and nursing home personnel, masking its true extent and clinical impact and reducing the opportunity for effective management. Assessment tools with cue words for continence status significantly improve identification of UI in nursing homes and increase the opportunity for effective management (Palmer, McCormick, Langford, et al., 1992).

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Risk Factors and Prevention

The incidence of incontinence is sufficiently high that the development of an effective prevention program would reduce new cases of incontinence in community-dwelling women alone approximately 50,000 cases annually (Siu, Beers, and Morgenstern, 1993). There is good evidence that specific risk factors for incontinence can be both identified and remedied with targeted interventions. However, no controlled clinical trial data exist showing that these interventions reduce incontinence incidence, severity, or prevalence. Table 1 provides a summary of risk factors associated with incontinence that have been documented in the literature. Only one reference has been listed for each risk factor, although in most cases multiple studies have described the same factor. Several of the studies described interventions that have modified these risk factors successfully.

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Risk factors associated with incontinence

Risk Factor Reference
Immobility/chronic degenerative disease Ouslander, Palmer, Rovner, et al., 1993; Adams, Lorish, Cushing, et al., 1994
Impaired cognition Morris, Browne, and Saltmarche, 1992; Skelly and Flint, 1995
Medications Dwyer and Teele, 1992
Morbid obesity Bump and McClish, 1994
Diuretics Diokno, Brock, Herzog, el al., 1990
Smoking Bump and McClish, 1994
Fecal impaction Resnick and Yalla, 1985
Delirium Resnick, 1988
Low fluid intake Colling, Owen, and McCreedy, 1994
Environmental barriers Wyman, Elswick, Ory, et al., 1993
High-impact physical activities Nygaard, Thompson, Svengalis, et al., 1994
Diabetes Appell and Baum, 1990
Stroke Benbow, Sangster, and Barer, 1991
Estrogen depletion Burns, Nochajski, and Pranifoff, 1993
Pelvic muscle weakness Burns, Nochajski, and Pranifoff, 1993
Childhood nocturnal enuresis Moore, Richmond, and Parys, 1991
Race Burgio, Matthews, and Engel, 1991
Pregnancy/vaginal delivery/ episiotomy Foldspang, Mommsen, Lam, et al., 1992; Klein, Gauthier, Robbins, et al., 1994

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Costs

A recent estimate of the direct costs of caring for persons of all ages with incontinence is $11.2 billion annually in the community and $5.2 billion in nursing homes (based on 1994 dollars) (Hu, 1994). This cost estimate is more than 60 percent greater than that for the cost of services in the medical care sector. Data show that costs of providing care for UI vary widely (Baker and Bice, 1995; Hu, Gabelko, Weiss, et al., 1994).

The guideline does not address specific reimbursement issues, which are being evaluated by other groups (National Kidney and Urologic Diseases Advisory Board, 1994).

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Urinary Incontinence: Types, Definitions, Pathophysiology and Symptoms (**)

(**)Managing Acute and Chronic Urinary Incontinence, U.S. Department of Health and Human Services Public Health Service, Agency for Health Care Policy and Research, AHCPR Publication No. 96-0686

Type of Urinary Incontinence Definition Pathophysiology Symptoms and signs
Urge Incontinence Involuntary loss of urine associated with a strong sensation of urinary urgency Involuntary detrusor (bladder) contractions (detrusor instability (DI).

Detrusor hyperactivity with impaired bladder contractility (DHIC).

Involuntary sphincter relaxation.

Loss of urine with an abrupt and strong desire to void; usually loss of urine on way to bathroom.

DHIC-elevated post-void residual (PVR) volume.

Involuntary loss of urine (without symptoms).

Stress Incontinence

 

 

 

Urethral sphincter failure usually associated with increased intra-abdominal pressure. Urethral hypermobility due to anatomic changes or defects such as fascial detachments (hypermobility)

Intrinsic urethral sphincter deficiency (ISD), failure of the sphincter at rest.

Small amount of urine loss during coughing, sneezing, laughing, or other physical activities.

Continuous leak at rest or with minimal exertion (postural changes).

Mixed Incontinence Combination of urge and stress UI. Combination of urge and stress features as above.

Common in women, especially older women.

Combinations of urge and stress UI symptoms as above. One symptom (urge or stress) often more bothersome to the patient than the other.
Overflow Incontinence Bladder overdistention. Acontractile detrusor.

Hypotonic or underactive detrusor secondary to drugs, fecal impaction, diabetes, lower spinal cord injury, or disruption of motor innervation of the detrusor muscle.

In men -- secondary obstruction due to prostatic hyperplasia, prostatic carcinoma, or urethral stricture.

In women -- obstruction due to severe genital prolapse or surgical overcorrection of urethral detachment.

Variety of symptoms, including frequent or constant dribbling or urge or stress incontinence symptoms, as well as urgency and frequent urination.
Functional Incontinence Chronic impairments of physical and/or cognitive functioning. Chronic functional and mental disabilities. Urge incontinence or functional limitations.
Unconscious or reflex Incontinence Neurologic dysfunction Decreased bladder compliance with risk of vesicoureteral reflux and hydronephrosis.

Secondary to radiation cystitis, inflammatory bladder conditions, radical pelvic surgery, or myelomenigocele.

In many nonneurogenic cases, no demonstrable DI.

Postmicturitional or continual incontinence. Severe urgency with bladder hypersensitivity (sensory urgency).

 

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